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Clinical Trial Finder
Observational Closed to Enrollment
MAYFLOWERS: Study of pregnancy in women with cystic fibrosis (MAYFLOWERS-OB-20)
This observational study will evaluate the effects of CFTR modulators on women with CF during and after pregnancy. CFTR modulators are intended to help CFTR protein function closer to normal.
This is a multi-center study that will take place at 40 care centers across the U.S. Women will be enrolled in the first trimester of pregnancy and assessed every 3 months during pregnancy into the first year after delivery, and then every 6 months for an additional year. Researchers will study changes in lung function to better understand how CFTR modulators affect women during and after pregnancy.This study will require lung function tests and/or other measurements.
Eligibility
See other primary eligibility criteria for more information.
-
Age:
16 Years and Older -
Mutation(s):
No Mutation Requirement -
FEV1% Predicted:
No FEV1 Limit
For more information about the results of this study and where it was conducted, visit ClinicalTrials.gov.
Other Primary Eligibility Criteria
Currently pregnant (i.e., either positive in-home pregnancy test with an absence of negative confirmatory pregnancy test or positive in-clinic pregnancy test). Planning to continue with pregnancy.
Study Design
-
Study Type: ?more info
Observational -
Randomized Study: ?more info
No -
Placebo Controlled: ?more info
No -
Length of Participation:
35 months -
Number of Study Visits:
9
Additional Information
-
Phase: ?more info
Not Applicable -
Study Sponsor: ?more info
Taylor-Cousar, Jennifer -
Study Drugs:
N/A
Study Sites
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Closed to Enrollment
Alabama
University of Alabama at Birmingham, Birmingham, AL 35233
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Closed to Enrollment
Arkansas
University of Arkansas for Medical Sciences, Little Rock, AR 72205
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Closed to Enrollment
California
University of California San Diego, La Jolla, CA 92037
-
Closed to Enrollment
Colorado
National Jewish Health, Denver, CO 80206
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Closed to Enrollment
Florida
University of Florida, Gainesville, FL 32610
-
Closed to Enrollment
Florida
Joe DiMaggio Children's Hospital, Hollywood, FL 33021
-
Closed to Enrollment
Georgia
Emory University, Atlanta, GA 30324
-
Closed to Enrollment
Idaho
Saint Luke's Cystic Fibrosis Center of Idaho, Boise, ID 83702
-
Closed to Enrollment
Indiana
Indiana University Medical Center, Indianapolis, IN 46202
-
Closed to Enrollment
Kansas
University of Kansas Medical Center, Kansas City, KS 66160
-
Closed to Enrollment
Kentucky
University of Kentucky, Lexington, KY 40536
-
Closed to Enrollment
Louisiana
Tulane University, Metairie, LA 70006
-
Closed to Enrollment
Maryland
Johns Hopkins University, Baltimore, MD 21205
-
Closed to Enrollment
Massachusetts
Massachusetts General Hospital, Boston, MA 02114
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Closed to Enrollment
Massachusetts
Boston Children's Hospital, Brigham & Women's Hospital, Boston, MA 02115
-
Closed to Enrollment
Michigan
University of Michigan Health System, Ann Arbor, MI 48109
-
Closed to Enrollment
Michigan
Corewell Health, Grand Rapids, MI 49546
-
Closed to Enrollment
Minnesota
The Minnesota Cystic Fibrosis Center, Minneapolis, MN 55455
-
Closed to Enrollment
Missouri
Washington University School of Medicine, St. Louis, MO 63110
-
Closed to Enrollment
Nebraska
University of Nebraska Medical Center, Omaha, NE 68198
-
Closed to Enrollment
New York
Columbia University Cystic Fibrosis Program, New York, NY 10032
-
Closed to Enrollment
New York
SUNY Upstate Medical University, Syracuse, NY 13210
-
Closed to Enrollment
New York
The Cystic Fibrosis Center of Western New York, Buffalo, NY 14203
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Closed to Enrollment
New York
University of Rochester Medical Center Strong Memorial, Rochester, NY 14609
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Closed to Enrollment
North Carolina
University of North Carolina at Chapel Hill, Chapel Hill, NC 27514
-
Closed to Enrollment
Ohio
University of Cincinnati Medical Center, Cincinnati, OH 45267
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Closed to Enrollment
Ohio
Nationwide Children's Hospital, Columbus, OH 43205
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Closed to Enrollment
Ohio
Cleveland Clinic Cystic Fibrosis Program, Cleveland, OH 44195
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Closed to Enrollment
Ohio
Rainbow Babies and Children's Hospital/University Hospitals Cleveland Medical Center, Cleveland, OH 44106
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Closed to Enrollment
Oregon
Oregon Health Sciences University, Portland, OR 97239
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Closed to Enrollment
Pennsylvania
University of Pennsylvania, Philadelphia, PA 19104
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Closed to Enrollment
Pennsylvania
University of Pittsburgh Medical Center, Pittsburgh, PA 15224
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Closed to Enrollment
South Carolina
Medical University of South Carolina, Charleston, SC 29425
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Closed to Enrollment
Tennessee
Vanderbilt University Medical Center, Nashville, TN 37232
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Closed to Enrollment
Texas
Baylor College of Medicine, Houston, TX 77030
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Closed to Enrollment
Texas
University of Texas Southwestern, Dallas, TX 75390
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Closed to Enrollment
Utah
Adult Cystic Fibrosis Center at the University of Utah, Salt Lake City, UT 84112
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Closed to Enrollment
Washington
University of Washington Medical Center, Seattle, WA 98195
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Closed to Enrollment
Wisconsin
University of Wisconsin, Madison, WI 53792
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Closed to Enrollment
Wisconsin
Froedtert & Medical College of Wisconsin, Milwaukee, WI 53226
Eligibility
See other primary eligibility criteria for more information.
-
Age:
16 Years and Older -
Mutation(s):
No Mutation Requirement -
FEV1% Predicted:
No FEV1 Limit
For more information about the results of this study and where it was conducted, visit ClinicalTrials.gov.
Other Primary Eligibility Criteria
Currently pregnant (i.e., either positive in-home pregnancy test with an absence of negative confirmatory pregnancy test or positive in-clinic pregnancy test). Planning to continue with pregnancy.

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