Drug Development Pipeline
Inhaled molgramostim is a form of granulocyte macrophage-colony stimulating factor (GM-CSF). GM-CSF is a protein that occurs naturally in the human immune system and plays an important role in activating the immune system to kill bacteria and other infections. Because inhaled mogramostim helps to stimulate the part of the immune system that fights Nontuberculous mycobacteria (NTM), it may be able to help the body clear NTM infection.
A phase 2 study to test the effectiveness of inhaled mogramostim against NTM in adults with CF did not meet its primary endpoint. No further development in CF is planned at this time.
This program was sponsored by Savara. It was conducted within the CFF's Therapeutics Development Network.
Recent Inhaled Molgramostim Studies
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