Drug Development Pipeline
ABBV-2222 + ABBV-3067 + ABBV-576
Restore CFTR Protein
This program studyied a combination therapy combining three CFTR modulators, two correctors and a potentiator. Correctors are a type of modulator designed to fix the defective CFTR protein so that it can move to the proper place on the cell surface. Once CFTR protein reaches the cell surface, potentiators help facilitate the opening of the chloride channel to allow chloride and sodium (salt) to move in and out of the cell.
A phase 2 study to test the safety and effectiveness of this potential therapy was conducted. No further studies in CF are planned at this time.
This program was sponsored by Abbvie and conducted within the Therapeutics Development Network.
Recent ABBV-2222 + ABBV-3067 + ABBV-576 Studies
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