This program is working to develop a breath test to help doctors diagnose and monitor Pseudomonas aeruginosa infections in people with cystic fibrosis.

A Pseudomonas infection is usually diagnosed by culturing a sputum sample, but it can be difficult to obtain these samples from children or from people with CF who are taking modulator therapies that help clear mucus from the lungs. Owlstone’s breath test aims to provide a way to detect new Pseudomonas infections without relying on sputum. Additionally, the test is intended to enable care teams to monitor chronic infections in people with CF.

Status

Preclinical laboratory studies are underway to test the feasibility of analyzing the breath to identify Pseudomonas lung infections and whether this technology can support longer term monitoring.

Sponsor

This program is sponsored by Owlstone Medical and is partially funded by the Cystic Fibrosis Foundation.