ALX-009 is a combination of two substances found naturally in the body, hypothiocyanite (OSCN-) and lactoferrin. Both of these molecules are part of the body’s natural immune system, but they are deficient in the airway surface liquid of people with CF. By adding both OSCN- and lactoferrin to the airways, ALX-009 may increase the ability of people with CF to fight bacteria without harming their body’s own cells. ALX-009 is delivered via inhalation.

Status

A Phase 1 study to test the safety and tolerability of ALX-009 was completed. No further development in CF is planned at this time.

Sponsor

This program was sponsored by Alaxia and partially funded by the Cystic Fibrosis Foundation.