Page Title
Drug Development Pipeline
Lenabasum (JBT-101)
Status
DiscontinuedTherapeutic Approach
Anti-Inflammatory
Lenabasum (JBT-101) is an oral drug that is aimed at promoting the resolution of inflammation. It is thought to increase production of anti-inflammatory molecules while reducing production of molecules that increase inflammation. Reduction of inflammation helps prevent permanent tissue damage in the lungs.
Status
A phase 2 trial of lenabasum did not meet its primary endpoint of decreasing pulmonary exacerbations in people with cystic fibrosis. No further development in CF is planned.
Sponsor
This program was sponsored by Corbus and partially funded by the Cystic Fibrosis Foundation. It was conducted within the Therapeutics Development Network.
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