Page Title
Drug Development Pipeline
Hypertonic Saline
Status
To PatientsTherapeutic Approach
Mucociliary Clearance
Hypertonic saline as an inhaled therapy is believed to increase hydration of airway surface liquid in people with CF, thereby improving mucus clearance.
Status
A Phase 3 study conducted in Australia showed beneficial effects of hypertonic saline on pulmonary health in people with CF ages 6 years and older. A Phase 2 study of hypertonic saline in preschool children is currently underway.
Sponsor
The program is fully funded through the Cystic Fibrosis Foundation and facilitated by the Therapeutics Development Network Coordinating Center.
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