Drug Development Pipeline
Lenabasum (JBT-101) is an oral drug that is aimed at promoting the resolution of inflammation. It is thought to increase production of anti-inflammatory molecules while reducing production of molecules that increase inflammation. Reduction of inflammation helps prevent permanent tissue damage in the lungs.
A phase 2 trial of lenabasum did not meet its primary endpoint of decreasing pulmonary exacerbations in people with cystic fibrosis. No further development in CF is planned.
This program was sponsored by Corbus and partially funded by the Cystic Fibrosis Foundation. It was conducted within the Therapeutics Development Network.
Recent Lenabasum (JBT-101) Studies
Closed to Enrollment
Phase 2 study of JBT-101 in people with CF (Corbus JBT101-CF-002)
Completed with Results
Phase 2 study of JBT-101 in people with CF (Corbus JBT101-CF-001)
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